P. Müller

Spatial and temporal characteristics of laboratory-induced Anopheles coluzzii swarms: shape, structure and flight kinematics

This study characterizes the spatial and temporal flight kinematics of Anopheles coluzzii swarms, showing stereotypic shape and density patterns and modeling swarm structure based on visual perception.

Transformation of the drug ibuprofen by Priestia megaterium: Reversible glycosylation and generation of hydroxylated metabolites

This paper identifies two main biotransformation pathways of ibuprofen by Priestia megaterium, including hydroxylation and reversible glycosylation, and shows their potential role in detoxification.

Beyond comparison: Brillouin microscopy and AFM-based indentation reveal divergent insights into the mechanical profile of the murine retina

This study compares Brillouin microscopy and AFM-based indentation to assess mechanical properties of murine retinal tissues, finding divergent results and highlighting their complementary nature.

Ergosterol mediates aggregation of natamycin in the yeast plasma membrane

This paper shows that ergosterol mediates natamycin aggregation in yeast plasma membranes, which underlies its antifungal activity and can be enhanced by sphingolipid inhibitors.

Tuning of granulopoietic signaling by de novo designed agonists

This paper designs and characterizes agonists that tune G-CSFR activity to bias granulopoiesis over proliferation, showing improved stability and selectivity compared to native G-CSF.

Synthesis and characterization of novel intrinsically fluorescent analogs of cholesterol with improved photophysical properties.

This paper presents novel intrinsically fluorescent cholesterol analogs with improved photophysical properties for live-cell imaging of sterol transport.

Sub-lethal exposure to chlorfenapyr reduces the probability of developing Plasmodium falciparum parasites in surviving Anopheles mosquitoes

This study shows that sub-lethal chlorfenapyr exposure reduces Plasmodium falciparum infection in pyrethroid-resistant mosquitoes.

RIG-I immunotherapy overcomes radioresistance in p53-positive malignant melanoma

This study shows that RIG-I ligands enhance radiation-induced tumor cell death and immunogenicity in melanoma, with p53 playing a key role in the synergy between RIG-I and radiation.

Twisting DNA by Salt

This study investigates how DNA twist changes with ion concentration and identity using single-molecule experiments and simulations, revealing trends in cation-specific effects on DNA structure.

Correlative all-optical quantification of mass density and mechanics of sub-cellular compartments with fluorescence specificity

This paper introduces FOB microscopy to measure sub-cellular density and mechanics with fluorescence specificity, revealing differences between nucleoplasm and cytoplasm.

SR7 - a dual function antisense RNA from Bacillus subtilis

The paper identifies SR7 as a dual-function antisense RNA in Bacillus subtilis that encodes a small protein, SR7P, which interacts with enolase and enhances RNase Y activity, affecting RNA degradation and stress survival.

Using real-time fluorescence and deformability cytometry and deep learning to transfer molecular specificity to label-free sorting

The human α-defensin-derived peptide HD5(1-9) inhibits cellular attachment and entry of human cytomegalovirus.

The paper identifies HD5(1-9), a defensin-derived peptide, as an inhibitor of HCMV cellular attachment and entry, with low toxicity.