Author

D. Wüstner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

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Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 2 Assay:imaging· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. D. Juhl· 2 shared G. Schneider· 2 shared M. Lehmann· 2 shared P. Müller· 2 shared P. Wessig· 2 shared S. Werner· 2 shared A. J. Foster· 1 shared A. Upadhyaya· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiophysics

A. D. Juhl

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5 papers

Recent·Most cited

Ergosterol mediates aggregation of natamycin in the yeast plasma membrane

M. Szomek, V. Akkerman, L. Lauritsen, H.-L. Walther, A. D. Juhl, K. Thaysen, J. M. Egebjerg, D. F. Covey, M. Lehmann, P. Wessig, A. J. Foster, B. Poolman, S. Werner, G. Schneider, P. Müller, D. Wüstner

This paper shows that ergosterol mediates natamycin aggregation in yeast plasma membranes, which underlies its antifungal activity and can be enhanced by sphingolipid inhibitors.

bioRxiv · Dec 5, 2023 · PreprintBiophysics

Synthesis and characterization of novel intrinsically fluorescent analogs of cholesterol with improved photophysical properties.

M. Lehmann, P. Reinholdt, M. Bashawat, H. A. Scheidt, S. Halder, D. di Prima, J. Kongsted, P. Müller, P. Wessig, D. Wüstner

This paper presents novel intrinsically fluorescent cholesterol analogs with improved photophysical properties for live-cell imaging of sterol transport.

bioRxiv · Nov 23, 2023Biophysics

Kinetic modelling of sterol transport between plasma membrane and endo-lysosomes based on quantitative fluorescence and X-ray imaging data

D. Wüstner, A. D. Juhl, J. Egebjerg, S. Werner, J. G. McNally, G. Schneider

The paper uses kinetic modeling of sterol transport data to show that NPC2 deficiency leads to lipid accumulation in LE/LYS intraluminal vesicles, supported by X-ray imaging.

bioRxiv · Jan 28, 2023Biophysics

Single-molecule tracking reveals two low-mobility states for chromatin and transcriptional regulators within the nucleus

K. Wagh, D. A. Stavreva, R. A. Jensen, V. Paakinaho, G. Fettweis, R. L. Schiltz, D. Wüstner, S. Mandrup, D. M. Presman, A. Upadhyaya, G. L. Hager

This study uses single-molecule tracking and machine learning to identify two low-mobility states of chromatin and transcriptional regulators, showing dynamic interactions and switching between states.

bioRxiv · Jul 25, 2022Biophysics

A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates

C. V. Hansen, H. J. Schroll, D. Wüstner

This paper introduces a computational method to analyze FLIP data and estimate transport parameters of polyglutamine protein aggregates in cells.

bioRxiv · Apr 17, 2018Biophysics