Pyruvate supports RET-dependent mitochondrial ROS production necessary to control Mycobacterium avium infection in human primary macrophages
L. M. Rost, C. Louet, P. Bruheim, T. H. FLO, A. Gidon
This study shows that pyruvate import into mitochondria drives ROS production, which helps control Mycobacterium avium infection in human macrophages.
bioRxiv · Feb 1, 2022Immunology