Author

L. N. Lessen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:microscopy & imaging analysis· 2 Organism:yeast· 2 Assay:cryo-EM· 1 Assay:CUT&Tag· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

R. Green· 2 shared A. Prabhakar· 1 shared A. R. Buskirk· 1 shared C. C.-C. Wu· 1 shared J. Cheng· 1 shared J. D. Puglisi· 1 shared J. Wang· 1 shared M. R. Lawson· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

R. Green

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2 papers

Recent·Most cited

Mechanisms that ensure speed and fidelity in eukaryotic translation termination

M. R. Lawson, L. N. Lessen, J. Wang, A. Prabhakar, N. C. Corsepius, R. Green, J. D. Puglisi

The paper uses single-molecule fluorescence assays to study eukaryotic translation termination dynamics in yeast, revealing a conserved multi-step process involving eRF1 and eRF3.

bioRxiv · Apr 1, 2021Biochemistry

Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts

P. Tesina, L. N. Lessen, R. Buschauer, J. Cheng, C. C.-C. Wu, O. Berninghausen, A. R. Buskirk, T. Becker, R. Beckmann, R. Green

This study identifies molecular mechanisms of translational stalling caused by inhibitory codon pairs and poly(A) tracts using in vitro biochemistry, ribosome profiling, and cryo-EM.

bioRxiv · Sep 4, 2019Biochemistry