L. O'Brien

Evaluation of the SARS-CoV-2 inactivation efficacy associated with buffers from three kits used on high-throughput RNA extraction platforms

This study evaluates the inactivation efficacy of SARS-CoV-2 using lysis buffers from three kits on two high-throughput RNA extraction platforms, showing that combining heat treatment with lysis buffers fully inactivates the virus.

Non-canonical Hedgehog signaling through L-type voltage gated Ca2+ channels controls CD8+ T cell killing

This study identifies L-type voltage gated Ca2+ channels as essential for Hedgehog signaling in CD8+ T cells, which is critical for their cytotoxic function.