Author

V. Carbonaro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Chandra· 1 shared A. G. Richter· 1 shared A. M. Condliffe· 1 shared A.-K. Stark· 1 shared C. Chilamakuri· 1 shared C. Kapeni· 1 shared E. Banham-Hall· 1 shared E. M. Hessel· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Chandra

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2 papers

Recent·Most cited

Non-canonical Hedgehog signaling through L-type voltage gated Ca2+ channels controls CD8+ T cell killing

J. Hanna, C. Kapeni, L. O'Brien, V. Carbonaro, F. Beke, C. Chilamakuri, M. de la Roche

This study identifies L-type voltage gated Ca2+ channels as essential for Hedgehog signaling in CD8+ T cells, which is critical for their cytotoxic function.

bioRxiv · Mar 1, 2021 · PreprintImmunology

PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

A.-K. Stark, A. Chandra, K. Chakraborty, R. Alam, V. Carbonaro, J. Clark, S. Sriskantharajah, G. Bradley, A. G. Richter, E. Banham-Hall, M. R. Clatworthy, S. Nejentsev, J. N. Hamblin, E. M. Hessel, A. M. Condliffe, K. Okkenhaug

This study identifies a PI3Kδ-driven B cell subset in the lungs that worsens Streptococcus pneumoniae infection independently of antibodies, and shows that inhibiting PI3Kδ improves survival.

bioRxiv · Mar 18, 2018Immunology