Author

A. Phelps

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

M. Jordana· 3 shared A. Fang· 2 shared J. F. Koenig· 2 shared K. Bruton· 2 shared N. P. H. Knudsen· 2 shared P. S. Andersen· 2 shared S. Waserman· 2 shared A. Ariaz· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

M. Jordana

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pathogenic IgE-fated memory B cell responses retain functional plasticity

K. Bruton, A. Phelps, A. Ariaz, A. Fang, T. Walker, J. Wen, S. S. Khavkine-Binstock, D. Della Libera, O. Mann-Delany, N. P. H. Knudsen, S. Gadkar, E. Grydziuszko, J. F. Koenig, A. Gagnon, S. Waserman, , M. Jordana

This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.

bioRxiv · Nov 28, 2023Immunology

A Distinct Phenotype of Polarized Memory B cell holds IgE Memory

J. F. Koenig, N. P. H. Knudsen, A. Phelps, K. Bruton, I. Hoof, G. Lund, D. D. Libera, A. Lund, L. Christensen, D. R. Glass, T. D. Walker, A. Fang, S. Waserman, M. Jordana, P. S. Andersen

The paper identifies a novel memory B cell subset, MBC2s, that holds allergen-specific IgE memory and contributes to IgE production in allergic diseases.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Single-dose respiratory mucosal delivery of next-generation viral-vectored COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2

S. Afkhami, M. R. D'Agostino, A. Zhang, H. D. Stacey, A. Marzok, A. Kang, R. Singh, J. Bavananthasivam, G. Ye, X. Luo, F. Wang, J. C. Ang, A. Zganiacz, U. Sankar, N. Kazhdan, , Z. Xing

This study evaluates a multivalent Ad-vectored vaccine delivered via respiratory mucosal route, showing robust protection against SARS-CoV-2 and variants in mice.

bioRxiv · Jul 16, 2021Immunology

Evaluation of the SARS-CoV-2 inactivation efficacy associated with buffers from three kits used on high-throughput RNA extraction platforms

R. E. Thom, L. Eastaugh, L. O'Brien, D. Ulaeto, J. S. Findlay, S. Smither, A. Phelps, H. Stapleton, K. A. Hamblin, S. A. Weller

This study evaluates the inactivation efficacy of SARS-CoV-2 using lysis buffers from three kits on two high-throughput RNA extraction platforms, showing that combining heat treatment with lysis buffers fully inactivates the virus.

bioRxiv · Apr 14, 2021Microbiology