Author

L. Pelzl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

F. Lang· 2 shared Y. Singh· 2 shared A. Cheng· 1 shared A. Dhariwal· 1 shared C. Trautwein· 1 shared D. S. Park· 1 shared D. Wallweiner· 1 shared H. Cao· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

F. Lang

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2 papers

Recent·Most cited

DJ-1 (Park7) affects the gut microbiome, metabolites, and development of Innate Lymphoid Cells (ILCs)

Y. Singh, C. Trautwein, A. Dhariwal, M. S. Salker, M. Alauddin, L. Zizmare, L. Pelzl, M. Feger, J. Matthes, N. Casadei, M. Föller, V. Pachauri, D. S. Park, T. W. Mak, J. S. Frick, , O. Riess

This study shows that DJ-1 deficiency in mice alters gut microbiome composition, increases inflammatory markers, and reduces innate lymphoid cells, potentially contributing to Parkinson's disease pathogenesis.

bioRxiv · Sep 19, 2019Immunology

Gut bacterial metabolite Urolithin A (UA) mitigates Ca2+ 1 entry inT cells by regulating miR-10a-5p

S. Zhang, T. Maghout, H. Cao, L. Pelzl, M. Salkere, A. Cheng, F. Lang, Y. Singh

This study shows that gut metabolite UA reduces T cell proliferation by increasing miR-10a-5p and decreasing Orai1/STIM1/STIM2 expression and SOCE in murine CD4+ T cells.

bioRxiv · Jan 29, 2018Immunology