Author

O. Riess

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

N. Casadei· 5 shared Y. Singh· 5 shared M. S. Salker· 4 shared S. Ossowski· 4 shared C. Trautwein· 2 shared Deutsche COVID-19 OMICS Initiative (DeCOI)· 2 shared R. Bajaj· 2 shared V. Hammer· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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5 shared papersImmunology

N. Casadei

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5 papers

Recent·Most cited

Comparative multi-OMICS single-cell atlas of five COVID-19 (rAdVV and mRNA) vaccines describe unique and distinct mechanisms of action

Y. Singh, A. Schulze-Selting, G. Gabernet, U. Ray, R. Bajaj, M. Ali, M. Loitz, V. Hammer, E. Buena-Atienza, C. Ruschil, J. Huebner, M. Kowarik, M. salker, N. Casadei, S. Nahnsen, , O. Riess

This study compares the mechanisms of action of five COVID-19 vaccines using multi-omics single-cell data, revealing distinct immune responses and cell-type-specific effects.

bioRxiv · Sep 12, 2022 · PreprintImmunology

Immune dynamics at single cell protein level after delta/omicron infection in COVID-19 vaccinated convalescent individuals

R. Bajaj, Z. Yang, V. Hammer, S. Poeschel, K. Beiber, M. S. Salker, N. Casadei, S. Ossowski, O. Riess, Y. Singh

This study examines immune dynamics at the protein level in vaccinated individuals infected with delta or omicron variants, finding reduced NK cells and increased T and B cells, and that booster doses reduce infection severity.

bioRxiv · Sep 5, 2022 · PreprintImmunology

Single-cell RNA sequencing highlights a reduced function of natural killer and cytotoxic T cells in recovered COVID-19 pregnant women

N. H. A. Aziz, M. S. Salker, A. K. Lankapalli, M. N. Shafiee, E. Kocak, S. P. Shekhar, O. Khalid, N. M. Kasim, A. Kalok, N. A. Fuad, S. Ossowski, N. Casadei, Deutsche COVID-19 OMICS Initiative (DeCOI), S. Y. Brucker, O. Riess, Y. Singh

This study uses single-cell RNA sequencing to show that SARS-CoV-2 infection reduces cytotoxic function in natural killer and CD8+ T cells in recovered pregnant women.

bioRxiv · Aug 18, 2022 · PreprintImmunology

SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells

Y. Singh, C. Trautwein, R. Fendel, N. Krickeberg, G. Berezhnoy, R. Bissinger, S. Ossowski, M. S. Salker, N. Casadei, O. Riess, The DeCOI

This study examines how SARS-CoV-2 infection affects CD8+ T cell cytotoxicity and immune cell metabolism in COVID-19 patients.

bioRxiv · Sep 4, 2020Immunology

DJ-1 (Park7) affects the gut microbiome, metabolites, and development of Innate Lymphoid Cells (ILCs)

Y. Singh, C. Trautwein, A. Dhariwal, M. S. Salker, M. Alauddin, L. Zizmare, L. Pelzl, M. Feger, J. Matthes, N. Casadei, M. Föller, V. Pachauri, D. S. Park, T. W. Mak, J. S. Frick, , O. Riess

This study shows that DJ-1 deficiency in mice alters gut microbiome composition, increases inflammatory markers, and reduces innate lymphoid cells, potentially contributing to Parkinson's disease pathogenesis.

bioRxiv · Sep 19, 2019Immunology