L. Richard-Parpaillon

This study shows that Polo kinase activity, regulated by Aurora A and B, controls cell division duration and prevents tumor formation in Drosophila neural stem cells by coupling mitotic progression with polarization.

The paper shows that peripheral microtubules and the Chromosome Passenger Complex are required for cortical centralspindlin recruitment, which ensures asymmetric furrow positioning in neural stem cells.

The paper identifies dTBCE's role in promoting mitotic spindle assembly by recruiting tubulin around chromatin in Drosophila.

This study identifies the Kinesin-1 activation mechanism by Ensconsin/MAP7, showing that the KBD domain binds and stimulates Kinesin-1 binding to Mts, with full-length Ensconsin enabling direct activation on microtubules.