Author

L. Rowley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

J. F. Bateman· 2 shared A. Bikovtseva· 1 shared A. J. Fosang· 1 shared A. S. DiChiara· 1 shared B. Crimeen-Irwin· 1 shared C. Angelucci· 1 shared C. B. Little· 1 shared D. Eyre· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPathology

J. F. Bateman

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Author profile →

3 papers

Recent·Most cited

The effect of carbamazepine on bone structure and strength in control and Osteogenesis Imperfecta (Col1a2 +/p.G610C) mice

M. Blank, N. E. McGregor, L. Rowley, L. H. Kung, B. Crimeen-Irwin, I. J. Poulton, E. C. Walker, J. H. Gooi, S. R. Lamande, N. Sims, J. F. Bateman

This study tests carbamazepine's effect on bone structure and strength in OI mice and controls, finding no benefit in OI mice but growth impairment in controls.

bioRxiv · Feb 23, 2022Pathology

XBP1s-Mediated Endoplasmic Reticulum Proteostasis Network Enhancement Can Selectively Improve the Folding and Secretion of an Osteogenesis Imperfecta-Causing Collagen-I Variant

A. S. DiChiara, N.-D. Doan, A. Bikovtseva, L. Rowley, V. Butty, M. Weis, D. Eyre, S. Lamande, J. F. Bateman, M. D. Shoulders

This study shows that activating the XBP1s pathway enhances collagen-I secretion from OI-causing G425S mutant fibroblasts without affecting wild-type collagen.

bioRxiv · Apr 15, 2021 · PreprintCell Biology

Cartilage microRNA dysregulation in mouse osteoarthritis overlaps with patient disease candidates

L. H. W. Kung, V. Ravi, L. Rowley, C. Angelucci, A. J. Fosang, K. M. Bell, C. B. Little, J. Bateman

The paper identifies microRNA dysregulation in a mouse osteoarthritis model and finds overlaps with human OA candidates, suggesting potential biomarkers and therapeutic targets.

bioRxiv · Mar 22, 2017Cell Biology