Author

L. S. Matheson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:development & morphogenesis· 3 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Turner· 5 shared F. Salerno· 3 shared C. W. J. Smith· 2 shared E. Monzon-Casanova· 2 shared G. Petkau· 2 shared M. Screen· 2 shared O. Gizlenci· 2 shared A. J. Howden· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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5 shared papersImmunology

M. Turner

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Author profile →

5 papers

Recent·Most cited

Zfp36l1 establishes the high affinity CD8 T cell response by directly linking TCR affinity to cytokine sensing

G. Petkau, T. Mitchell, M. Jones Evans, L. S. Matheson, F. Salerno, M. Turner

The paper shows ZFP36L1 links TCR affinity to cytokine sensing, promoting clonal expansion of high affinity CD8 T cells through IL2 competition.

bioRxiv · May 11, 2023 · PreprintImmunology

An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells

F. Salerno, A. J. Howden, L. S. Matheson, O. Gizlenci, M. Screen, H. Lingel, M. Brunner-Weinzierl, M. Turner

The paper integrates proteome and transcriptome data from mouse B cells to identify poised mRNAs and translational regulators involved in activation and antibody secretion.

bioRxiv · Dec 22, 2022Immunology

Polypyrimidine Tract Binding Protein 1 regulates the activation of mouse CD8 T cells

V. D'Angeli, E. Monzon-Casanova, L. S. Matheson, O. Gizlenci, G. Petkau, C. Gooding, R. V. Berrens, C. W. J. Smith, M. Turner

This study shows PTBP1 is essential for optimal expansion and effector function of antigen-specific CD8 T cells, regulating splicing, mRNA abundance, and NFAT protein nuclear accumulation.

bioRxiv · Mar 3, 2022Immunology

The RNA m6A binding protein YTHDF2 promotes the B cell to plasma cell transition.

D. Turner, A. Saveliev, F. Salerno, L. S. Matheson, M. Screen, H. Lawson, D. Wotherspoon, K. Kranc, M. Turner

The paper identifies YTHDF2 as an m6A binding protein that promotes B cell to plasma cell transition in vitro and in chimeric mice.

bioRxiv · Jul 21, 2021 · PreprintImmunology

Polypyrimidine Tract Binding Proteins are essential for B cell development

E. Monzon-Casanova, L. S. Matheson, K. Tabbada, K. Zarnack, C. W. J. Smith, M. Turner

This study shows PTBP1 and PTBP2 regulate B cell development by controlling cell cycle progression through mRNA splicing and kinase activity.

bioRxiv · Nov 12, 2019Immunology