Author

L. Sweeney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

C. C. Hart· 2 shared D. W. Hammers· 2 shared Y. i. Lee· 2 shared A. Houdusse· 1 shared E. G. Heimsath· 1 shared G. Gao· 1 shared J. A. Hammer· 1 shared J. Xie· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

C. C. Hart

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Potential limitations of micro-dystrophin gene therapy for Duchenne muscular dystrophy

C. C. Hart, Y. i. Lee, J. Xie, G. Gao, D. W. Hammers, L. Sweeney

This study evaluates micro-dystrophin gene therapy in a DMD mouse model, finding cardiac disease acceleration with one micro-dystrophin and potential benefits with another, highlighting the need for careful dosing.

bioRxiv · Oct 2, 2022Pharmacology & Toxicology

High-resolution structures of the actomyosin-V complex in three nucleotide states provide insights into the force generation mechanism

S. Pospich, L. Sweeney, A. Houdusse, S. Raunser

The paper reports high-resolution cryo-EM structures of actomyosin-V in three nucleotide states, revealing structural transitions and insights into force generation.

bioRxiv · Sep 7, 2021Biochemistry

Filopodia powered by class X myosin promote fusion of mammalian myoblasts

D. W. Hammers, C. C. Hart, M. K. Matheny, E. G. Heimsath, Y. i. Lee, J. A. Hammer, R. E. Cheney, L. Sweeney

This study identifies class X myosin (Myo10) as a driver of filopodia formation that promotes myoblast fusion in muscle development and regeneration.

bioRxiv · Jul 28, 2021Cell Biology