Author

J. A. Hammer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Research Focus:development & morphogenesis· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

X. Wu· 2 shared A. Cameron· 1 shared A. Fineberg· 1 shared A. P. Curd· 1 shared C. C. Hart· 1 shared C. M. Waterman· 1 shared D. Cole· 1 shared D. Coombs· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

X. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Myosin-5 varies its steps along the irregular F-actin track

A. Fineberg, Y. Takagi, K. Thirumurugan, J. Andrecka, N. Billington, G. Young, D. Cole, S. A. Burgess, A. P. Curd, J. A. Hammer, J. R. Sellers, P. Kukura, P. J. Knight

This study reveals that myosin-5 takes variable step lengths along F-actin tracks, adapting to angular disorder in the track structure.

bioRxiv · Jul 16, 2023Biophysics

A B cell actomyosin arc network couples integrin co-stimulation to mechanical force-dependent immune synapse formation

J. C. Wang, Y.-I. Yim, X. Wu, V. Jaumouille, A. Cameron, C. M. Waterman, J. H. Kehrl, J. A. Hammer

The paper shows that an actomyosin arc network formed by LFA-1:ICAM-1 interactions is essential for integrin-dependent immune synapse formation in B cells.

bioRxiv · Aug 12, 2021Immunology

Filopodia powered by class X myosin promote fusion of mammalian myoblasts

D. W. Hammers, C. C. Hart, M. K. Matheny, E. G. Heimsath, Y. i. Lee, J. A. Hammer, R. E. Cheney, L. Sweeney

This study identifies class X myosin (Myo10) as a driver of filopodia formation that promotes myoblast fusion in muscle development and regeneration.

bioRxiv · Jul 28, 2021Cell Biology

Arp2/3 complex-driven spatial patterning of the B cell receptor (BCR) enhances immune synapse formation, BCR signaling, and cell activation

M. Bolger-Munro, K. Choi, J. Scurll, L. Abraham, R. Chappell, D. Sheen, M. Dang-Lawson, X. Wu, J. J. Priatel, D. Coombs, J. A. Hammer, M. R. Gold

The paper shows that Arp2/3 complex-driven spatial reorganization of BCR microclusters enhances immune synapse formation, BCR signaling, and B cell activation in response to membrane-bound antigens.

bioRxiv · Apr 30, 2019Immunology