Author

L. Valcarcel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

A. Carracedo· 1 shared A. Loizaga· 1 shared A. M. Aransay· 1 shared A. Macchia· 1 shared A. R. Cortazar· 1 shared A. Santos· 1 shared A. Schaub· 1 shared D. Olaverri-Mendizabal· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Carracedo

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2 papers

Recent·Most cited

Synthetic lethality in large-scale integrated metabolic and regulatory network models of human cells

N. Barrena, L. Valcarcel, D. Olaverri-Mendizabal, I. Apaolaza, F. J. Planes

The paper extends genetic Minimal Cut Sets (gMCS) to integrate metabolic and regulatory networks, identifying synthetic lethal gene pairs in human cancer cell lines.

bioRxiv · Jan 27, 2023Cancer Biology

Integrative analysis of transcriptomic and clinical data uncovers the tumor suppressive activity of MITF in prostate cancer.

L. Valcarcel, A. Macchia, N. Martin, A. R. Cortazar, A. Schaub, M. Pujana, S. Fernandez, I. Lacasa, A. Santos, A. Loizaga, M. Unda, I. Hermanova, I. Astobiza, M. Graupera, J. Starkova, , V. Torrano

The paper identifies MITF as a tumor suppressor in prostate cancer and reveals CRYAB as a direct target mediating its suppressive activity through integrative transcriptomic and clinical analysis.

bioRxiv · Aug 14, 2018Cancer Biology