Author

N. Martin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Microbiology· 3 Cell Biology· 2 Plant Biology· 2 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 11 Organism:human· 7 Approach:statistical model· 6 Research Focus:cell signaling & trafficking· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3

Frequent Co-Authors

B. Karim· 3 shared K. Saylor· 3 shared P. F. Johnson· 3 shared S. Basu· 3 shared B. Luke· 2 shared J. Salotti· 2 shared S. Lockett· 2 shared S. Misra· 2 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

B. Karim

Mutual co-authors in cluster

Author profile →

15 papers

Recent·Most cited

Attenuating ABHD17 isoforms augments the S-acylation and function of NOD2 and a subset of Crohns disease-associated NOD2 variants.

C. Dixon, N. Martin, M. Niphakis, B. Cravatt, G. D. Fairn

This study identifies ABHD17 isoforms as deacylases of NOD2, showing that inhibiting them enhances NOD2 membrane localization and function in Crohn's disease-associated variants.

bioRxiv · Dec 20, 2023Immunology

Phenotypic and genomic characterization of Bacillus sensu lato for their biofertilization effect and plant growth promotion features in soybean plants

P. Torres, N. Altier, E. Beyhaut, N. Martin, P. Fresia, S. Garaycochea, E. Abreo

The paper characterizes Bacillus sensu lato strains for their ability to mineralize phosphorus and promote soybean growth, identifying specific strains with enhanced biofertilization properties.

bioRxiv · Sep 5, 2023 · PreprintMicrobiology

Aging affects reprogramming of murine pulmonary capillary endothelial cells after lung injury

M. Truchi, M. Gautier-Isola, G. Savary, H. Cadis, C. Scribe, A. Baeri, A. Lingampally, V. Magnone, C. Girard-Riboulleau, M.-J. Arguel, C. de Schutter, J. Fassy, N. Boukrout, R. Larrue, N. Martin, , B. Mari

This study compares transcriptomic changes in pulmonary capillary endothelial cells from young and aged mice after lung injury, finding age-related differences in resolution and fibrotic signatures.

bioRxiv · Jul 11, 2023 · PreprintPathology

High-resolution mass spectrometry reveals environmentally relevant uptake, elimination, and metabolic alterations following early embryonic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in zebrafish

M. E. Kossack, K. Manz, N. Martin, K. D. Pennell, J. Plavicki

This study quantifies TCDD uptake and elimination in zebrafish embryos and identifies metabolic pathway disruptions linked to brain development.

bioRxiv · May 4, 2022 · PreprintPharmacology & Toxicology

CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS and NRAS mutant cancers

S. Basu, B. Luke, B. Karim, N. Martin, S. Lockett, S. Das, T. Andresson, K. Saylor, S. Kozlov, L. Bassel, D. Esposito, M. Galloux, P. F. Johnson

This study identifies TOLLIP as a critical adaptor for CK2 signaling from perinuclear endosomes in KRAS and NRAS mutant cancers, showing its role in tumor proliferation and progression.

bioRxiv · Apr 5, 2022 · PreprintCancer Biology

3'UTR-dependent dynamic changes in TP53 mRNA localization regulate p53 tumor suppressor activity

L. Hu, S. Misra, B. Karim, S. Kuhn, J. Salotti, S. Basu, N. Martin, K. Saylor, P. F. Johnson

This study shows that 3'UTR sequences of TP53 mRNA regulate its localization and activity by modulating CK2 phosphorylation and AMPK2/HuR dynamics.

bioRxiv · Apr 4, 2022 · PreprintCancer Biology

3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells

J. Salotti, N. Asif, S. Basu, A. Das, M. Yang, B. Karim, K. Saylor, N. Martin, D. A. Scheiblin, S. Misra, B. Luke, T. Andresson, S. Lockett, L. Tessarollo, P. F. Johnson

This study identifies a mechanism where 3'UTR-directed mRNA decay inhibits C/EBPβ activation, suppressing senescence in tumor cells and promoting tumor progression.

bioRxiv · Mar 29, 2022Cancer Biology

Cholesterol biosynthetic pathway induces cellular senescence through ERRa

D. V. Ziegler, M. Vernier, J. Czarnecka-Herok, C. Scholtes, C. Machon, J. Guitton, J. Rieusset, V. Giguere, N. Martin, D. Bernard

This study shows the mevalonate pathway promotes cellular senescence via ERRα, causing mitochondrial dysfunction, ROS, DNA damage, and p53-dependent senescence.

bioRxiv · Oct 20, 2021Cell Biology

DEVELOPMENT OF A SOYBEAN MATURITY PREDICTION MODEL FOR SOYBEAN GROWN IN AFRICAN ENVIRONMENTS

G. Marcillo, N. Martin, B. Diers, M. S. Da Fonseca, E. Leles

The paper develops a soybean maturity prediction model using environmental and geographic data to predict time-to-maturity within 10 days of observed values in African environments.

bioRxiv · Mar 9, 2021Plant Biology

Synthetic algal-bacteria consortia for space-efficient microalgal growth in a simple hydrogel system

N. Martin, T. Bernat, J. Dinasquet, A. Stofko, A. Damon, D. Deheyn, F. Azam, J. Smith, M. P. Davey, A. G. Smith, S. Vignolini, D. Wangpraseurt

This study develops a hydrogel system with algal-bacterial consortia that enhances microalgal growth rates by 3-fold compared to algae alone.

bioRxiv · Mar 1, 2021Microbiology

Chromatin accessibility changes at intergenic regions associates with ovarian cancer drug resistance

J. Gallon, E. Loomis, E. Curry, N. Martin, L. Brody, I. Garner, R. Brown, J. M. Flanagan

The paper examines chromatin accessibility changes in ovarian cancer cell lines resistant to platinum-based chemotherapy, finding intergenic region alterations linked to drug resistance and Pt-adduct distribution.

bioRxiv · Feb 24, 2021Cancer Biology

A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells

R. L. Tiwari, P. Mishra, N. Martin, N. O. George, V. Sakk, K. Soller, K. Nalapareddy, K. Nattamai, K. S. Kochanek, M. C. Florian, H. Geiger

This study identifies a Wnt5a-Cdc42 signaling axis that regulates hair-follicle stem cell aging and rejuvenation, showing that inhibiting Cdc42 activity restores canonical Wnt signaling and promotes hair regeneration.

bioRxiv · Oct 22, 2020Cell Biology

Targeted metagenomic sequencing enhances the identification of pathogens associated with acute infection.

C. Goh, T. Golubchik, M. A. Ansari, M. de Cesare, A. Trebes, I. Elliott, D. Bonsall, P. Piazza, A. Brown, H. Slawinski, N. Martin, S. Defres, M. J. Griffiths, J. E. Bray, M. C. Maiden, , R. Bowden

Castanet, a targeted metagenomic sequencing method, improves pathogen detection in clinical samples by combining sensitivity with cost-effectiveness and broad organism coverage.

bioRxiv · Jul 28, 2019 · PreprintMicrobiology

Integrative analysis of transcriptomic and clinical data uncovers the tumor suppressive activity of MITF in prostate cancer.

L. Valcarcel, A. Macchia, N. Martin, A. R. Cortazar, A. Schaub, M. Pujana, S. Fernandez, I. Lacasa, A. Santos, A. Loizaga, M. Unda, I. Hermanova, I. Astobiza, M. Graupera, J. Starkova, , V. Torrano

The paper identifies MITF as a tumor suppressor in prostate cancer and reveals CRYAB as a direct target mediating its suppressive activity through integrative transcriptomic and clinical analysis.

bioRxiv · Aug 14, 2018Cancer Biology

A systems biology approach to explore the impact of maple tree dormancy release on sap variation and maple syrup quality

G. Q. Nguyen, N. Martin, M. Jain, L. Lagace, C. Landry, M. Filteau

The paper investigates sap composition changes during maple tree dormancy release and links them to syrup quality and the buddy defect using amino acid analysis and yeast competition assays.

bioRxiv · Jun 4, 2018Plant Biology