Persistent confined migration confers permanent nuclear and functional changes in migrating cells.
A. de Lope-Planelles, R. Gonzalez-Novo, E. Madrazo, H. Zamora-Carreras, V. Torrano, H. Lopez-Menendez, P. Roda-Navarro, F. Monroy, J. Redondo-Munoz
The paper shows that persistent confined migration causes permanent nuclear and functional changes in cells, including lamin B1 redistribution and altered DNA repair.
bioRxiv · Jan 5, 2023 · PreprintCell Biology