Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics
V. I. P. Keizer, S. Grosse-Holz, M. Woringer, L. Zambon, K. Aizel, M. Bongaerts, L. Kolar-Znika, V. F. Scolari, S. Hoffmann, E. J. Banigan, L. A. Mirny, M. Dahan, D. Fachinetti, A. Coulon
The paper uses magnetic forces to manipulate a genomic locus in live human cells, revealing chromatin's viscoelastic properties and challenging the gel-like model.
bioRxiv · Apr 20, 2021Biophysics