Author

K. Aizel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:Hi-C· 1

Frequent Co-Authors

M. Bongaerts· 2 shared A. Coulon· 1 shared A. El Haj· 1 shared A. Jan· 1 shared A. P. Leis· 1 shared C. C. Kosasih· 1 shared C. J. Morton· 1 shared C. Menager· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

M. Bongaerts

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structures of the interleukin 11 signalling complex reveal dynamics of gp130 extracellular domains and the inhibitory mechanism of a cytokine variant

R. D. Metcalfe, E. Hanssen, K. Y. Fung, K. Aizel, C. C. Kosasih, C. O. Zlatic, L. Doughty, C. J. Morton, A. P. Leis, M. W. Parker, P. R. Gooley, T. L. Putoczki, M. D. W. Griffin

This study presents cryo-EM and crystal structures of the IL-11 signalling complex, revealing dynamics of gp130 and the inhibitory mechanism of a cytokine variant.

bioRxiv · Jul 21, 2022Cell Biology

Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics

V. I. P. Keizer, S. Grosse-Holz, M. Woringer, L. Zambon, K. Aizel, M. Bongaerts, L. Kolar-Znika, V. F. Scolari, S. Hoffmann, E. J. Banigan, L. A. Mirny, M. Dahan, D. Fachinetti, A. Coulon

The paper uses magnetic forces to manipulate a genomic locus in live human cells, revealing chromatin's viscoelastic properties and challenging the gel-like model.

bioRxiv · Apr 20, 2021Biophysics

Parallelized manipulation of adherent living cells by magnetic nanoparticles-mediated forces

M. Bongaerts, K. Aizel, E. Secret, A. Jan, T. Nahar, F. Raudzus, S. Neumann, N. Telling, R. Heumann, J.-M. Siaugue, C. Menager, J. Fresnais, C. Villard, A. El Haj, J. Piehler, , M. Coppey

This study demonstrates that magnetic nanoparticle-mediated forces from micro-magnetic pillars can direct cell migration and neurite outgrowth in adherent cells.

bioRxiv · Jul 21, 2020Bioengineering