Author

S. Grosse-Holz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:Bayesian inference· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

A. Coulon· 2 shared L. Mirny· 2 shared A. Jha· 1 shared A. S. Hansen· 1 shared C. Cattoglio· 1 shared C. Zechner· 1 shared D. Fachinetti· 1 shared E. J. Banigan· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiophysics

A. Coulon

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Author profile →

3 papers

Recent·Most cited

Scale-free models of chromosome structure, dynamics, and mechanics

S. Grosse-Holz, L. Mirny, A. Coulon

The paper develops a theoretical framework to analyze scaling relationships in chromosome structure, dynamics, and mechanics, identifying models consistent with observed exponents and proposing new experiments.

bioRxiv · Apr 14, 2023Biophysics

Dynamics of CTCF and cohesin mediated chromatin looping revealed by live-cell imaging

M. Gabriele, H. B. Brandao, S. Grosse-Holz, A. Jha, G. M. Dailey, C. Cattoglio, T.-H. S. Hsieh, L. Mirny, C. Zechner, A. S. Hansen

This study uses live-cell imaging to show that chromatin loops at the Fbn2 TAD are rare and dynamic, challenging the notion of stable TADs.

bioRxiv · Dec 12, 2021Biophysics

Live-cell micromanipulation of a genomic locus reveals interphase chromatin mechanics

V. I. P. Keizer, S. Grosse-Holz, M. Woringer, L. Zambon, K. Aizel, M. Bongaerts, L. Kolar-Znika, V. F. Scolari, S. Hoffmann, E. J. Banigan, L. A. Mirny, M. Dahan, D. Fachinetti, A. Coulon

The paper uses magnetic forces to manipulate a genomic locus in live human cells, revealing chromatin's viscoelastic properties and challenging the gel-like model.

bioRxiv · Apr 20, 2021Biophysics