Author

L. Zein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Nist· 1 shared B. Wilke· 1 shared C. Behrends· 1 shared C. Borgel· 1 shared C. Scheuer· 1 shared D. Balta· 1 shared F. Zunke· 1 shared H. Swoboda· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Nist

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

L. Zein, M. Dietrich, D. Balta, V. Bader, C. Scheuer, S. Zellner, N. Weinelt, J. Vandrey, M. C. Mari, C. Behrends, F. Zunke, K. F. Winklhofer, S. J. L. van Wijk

This study shows that linear ubiquitination at damaged lysosomes activates NF-κB and promotes cell survival through lysophagy.

bioRxiv · Oct 6, 2023 · PreprintCell Biology

Haptoglobin buffers lipopolysaccharides to safeguard against aberrant NFκB activation

L. Zein, J. Grossmann, H. Swoboda, C. Borgel, B. Wilke, S. Awe, A. Nist, T. Stiewe, O. Stehling, S.-A. Freibert, T. Adhikary, H.-R. Chung

This study shows haptoglobin binds and buffers lipopolysaccharides to delay NFκB activation in macrophages, suggesting its role in preventing aberrant inflammation.

bioRxiv · Nov 22, 2022 · PreprintImmunology