Author

N. Weinelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. J. L. van Wijk· 2 shared B. Jeiler· 1 shared B. Rotter· 1 shared C. Behrends· 1 shared C. Scheuer· 1 shared D. Balta· 1 shared F. Pampaloni· 1 shared F. Zunke· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

S. J. L. van Wijk

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2 papers

Recent·Most cited

Linear ubiquitination at damaged lysosomes induces local NF-κB activation and controls cell survival

L. Zein, M. Dietrich, D. Balta, V. Bader, C. Scheuer, S. Zellner, N. Weinelt, J. Vandrey, M. C. Mari, C. Behrends, F. Zunke, K. F. Winklhofer, S. J. L. van Wijk

This study shows that linear ubiquitination at damaged lysosomes activates NF-κB and promotes cell survival through lysophagy.

bioRxiv · Oct 6, 2023 · PreprintCell Biology

Species-specific LUBAC-mediated M1 ubiquitination regulates necroptosis by segregating the cellular distribution and fate of activated MLKL

N. Weinelt, K. N. Waechtershaeuser, S. Smith, G. Andrieux, T. Das, B. Jeiler, J. Roedig, L. Feist, B. Rotter, M. Boerries, F. Pampaloni, S. J. L. van Wijk

The paper identifies LUBAC-mediated M1 ubiquitination as a species-specific checkpoint regulating necroptosis by controlling MLKL membrane accumulation in human cells and organoids.

bioRxiv · Dec 8, 2022 · PreprintCell Biology