Author

L. Zhan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:plant physiology & development· 1

Frequent Co-Authors

A. M. Zelazny· 1 shared A. Radaic· 1 shared C. J. Lyon· 1 shared C. Qin· 1 shared C. Tafolla· 1 shared D. Ding· 1 shared E. V. Koonin· 1 shared F. Zhou· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 4 mutual co-author links

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1 shared paperMicrobiology

A. M. Zelazny

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Widespread PRC barrel proteins play critical roles in archaeal cell division

S. Zhao, K. Makarova, W. Zheng, Y. Liu, L. Zhan, Q. Wan, H. Gong, M. Krupovic, J. Lutkenhaus, X. Chen, E. V. Koonin, S. Du

This study identifies three PRC barrel proteins in Haloferax volcanii essential for archaeal cell division, showing their conservation and role in division across haloarchaea.

bioRxiv · Mar 28, 2023 · PreprintMicrobiology

Formulation of substrates with agricultural and forestry wastes for Camellia oleifera Abel seedling cultivation

J. Zhang, N. Wang, F. Zhou, X. Yao, X. Zhang, L. Zhan, J. Li

The paper evaluates five compost-based substrates for Camellia oleifera seedling cultivation, finding that a specific combination yields optimal growth and survival rates.

bioRxiv · Mar 14, 2022 · PreprintPlant Biology

Treponema denticola dentilisin triggered TLR2/MyD88 activation upregulates a tissue destructive program involving MMPs via Sp1 in human oral cells

S. Ganther, A. Radaic, N.-Y. N. Chang, C. Tafolla, L. Zhan, J. C. Fenno, Y. Kapila

This study shows T. denticola dentilisin activates TLR2/MyD88 to upregulate MMPs via Sp1, promoting tissue destruction in periodontal disease.

bioRxiv · Jan 18, 2021Microbiology

Acute noise causes down-regulation of ECM protein expression in guinea pig cochlea

M. Shi, L. Shi, D. Ding, Y. Hu, G. Qi, L. Zhan, Y. Zhu, P. Lv, N. Yu

This study uses proteomics to identify down-regulated ECM proteins in guinea pig cochleae after noise exposure, linking them to hearing loss mechanisms.

bioRxiv · Sep 27, 2020Immunology

IP-MS Analysis of ESX-5 and ESX-1 Substrates Enables Mycobacterial Species Identification

Q. Shu, M. Rajagopal, J. Fan, L. Zhan, X. Kong, Y. He, S. Rotcheewaphan, C. J. Lyon, W. Sha, A. M. Zelazny, T. Hu

The paper develops an IP-MS assay to identify slow-growing mycobacterial species in early MGIT cultures using species-specific antibodies.

bioRxiv · Jun 7, 2020 · PreprintMicrobiology

Downregulation of GPR183 on Infection Restricts the Early Infection and Intracellular Survival of Mycobacterium tuberculosis in Macrophage

J. Tang, Y. Shi, L. Zhan, C. Qin

This study shows that downregulating GPR183 in macrophages during Mtb infection limits bacterial survival, while overexpression or ligand stimulation promotes it.

bioRxiv · Nov 6, 2019Microbiology