Author

L.-L. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

M. Kellis· 3 shared J. Yang· 2 shared K. Galani· 2 shared M. Vamvini· 2 shared P. Nigro· 2 shared R. Middelbeek· 2 shared A. Chaudhri· 1 shared A. Lazar· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPhysiology

M. Kellis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

M. Maitituoheti, A. Shi, M. Tang, L.-L. Ho, C. Terranova, K. Galani, E. Keung, C. Creasy, M. Wu, J. Chen, N. Chen, A. Singh, A. Chaudhri, N. Anvar, G. Tarantino, , K. Rai

The paper identifies enhancer-based biomarkers of resistance to anti-PD-1 therapy in melanoma and suggests enhancer blockade combined with ICB as a potential strategy to improve treatment responses.

bioRxiv · Aug 31, 2022 · PreprintCancer Biology

Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)

P. Nigro, M. Vamvini, J. J. Yang, T. Caputo, L.-L. Ho, D. Papadopoulos, N. P. Carbone, R. Colin, J. He, H. F. Michael, J. D. White, J. Robidoux, R. Hickner, S. Nielsen, B. K. Pedersen, , L. J. Goodyear

This study shows that exercise training remodels iWAT ECM, increases vascularization and innervation, and alters adipocyte subpopulations in male mice.

bioRxiv · Aug 9, 2022Physiology

Single-cell dissection of obesity-exercise axis in adipose-muscle tissues

J. Yang, M. Vamvini, P. Nigro, L.-L. Ho, K. Galani, M. Alvarez, Y. Tanigawa, M. Laakso, L. Agudelo, P. Pajukanta, R. Middelbeek, K. Grove, L. Goodyear, M. Kellis

This study uses single-cell RNA sequencing to analyze the effects of exercise and diet on adipose and muscle tissues in mice, identifying key cell types and pathways involved in metabolic changes.

bioRxiv · Nov 22, 2021 · PreprintPhysiology