B. K. Pedersen

An ultrasound-guided biopsy technique for obtaining supraclavicular brown fat biopsies and preadipocytes

This paper describes an ultrasound-guided biopsy technique to collect supraclavicular brown fat and subcutaneous white fat from healthy individuals, and evaluates in vitro differentiation and gene expression of progenitor cells.

Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)

This study shows that exercise training remodels iWAT ECM, increases vascularization and innervation, and alters adipocyte subpopulations in male mice.

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

The paper shows that exercise increases circulating GDF15 levels, but this physiological increase does not suppress appetite or exercise motivation like pharmacological GDF15.

Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesity

The paper identifies a reduction in thermogenic genes but preserved brown adipose tissue identity in human obesity through transcriptomic analysis of BAT and WAT.

Proteomics-based comparative mapping of the human brown and white adipocyte secretome reveals EPDR1 as a novel batokine

The paper compares the secretomes of human brown and white adipocytes using proteomics, identifying EPDR1 as a novel batokine involved in thermogenesis and energy consumption.

A long-non-coding RNA, LINC00473, confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsiveness.

This study identifies LINC00473 as a key regulator of thermogenic adipocyte function, showing its role in enhancing cAMP responsiveness and mitochondrial activity.