The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney
Prasanna Katti, Praveena Prasad, Sepiso Kenias Masenga, Prasanna Venkhatesh, Zer Vue, Andrea Gail Marshall, Benjamin Rodriguez, Han Le, Edgar Garza Lopez, Alexandria C. Murphy, Brenita C. Jenkins, Ashlesha A. Kadam, Jianqiang Shao, Amber Crabtree, Pamela Martin, , Antentor Othrell Hinton Jr.
This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.
Aging Cell · May 1, 2026Peer-reviewedPhysiology