Author

Adam Roszczyk

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Organism:C. elegans· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley E. FrakesiD· 2 shared Karmen Mah· 2 shared Amber CrabtreeiD· 1 shared Andrea G. Marshall· 1 shared Annet KiraboiD· 1 shared Antentor HintoniD· 1 shared Antoine E. RouxiD· 1 shared Arin BhattacharjeeiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersNeuroscience

Ashley E. FrakesORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

The role of MICOS in modulating mitochondrial dynamics and structural changes in vulnerable regions of Alzheimer's Disease

Bryanna Shao, Bartosz Kula, Han Le, Prasanna Venkhatesh, Prasanna Katti, Andrea G. Marshall, Siddharth Chittaranjan, Suraj Thapilyal, Namdar Hari Kalpana, C. Nivedya, Adam Roszczyk, Harrison Mobley, Mason Killion, Emelina St John, Pamela Martin, , Nathan Smith

This study investigates how MICOS disruption affects mitochondrial structure and function in neurons vulnerable to Alzheimer's disease, linking these changes to early mitochondrial dysfunction and neuronal vulnerability.

bioRxiv · Apr 1, 2026 · PreprintNeuroscience

Parental origin of transgene determines recombination efficiency in GFAP-creERT2 mice

Karmen Mah, Adam Roszczyk, Ashley E. Frakes

The paper shows that the parental origin of the hGFAP-creERT2 transgene affects recombination efficiency in mice, with paternal inheritance leading to robust recombination and maternal inheritance causing little to none.

G3 Genes Genomes Genetics · Jun 17, 2025Peer-reviewedNeuroscience

A FMRF-amide peptide that regulates cell non-autonomous protein homeostasis in C. elegans.

Carrie A. Sheeler, Jacqueline Y. Lo, Daviana Menendez Escalera, Emmett Griffin‐Baldwin, Karmen Mah, Adam Roszczyk, Antoine E. Roux, Cynthia J. Kenyon, Jennifer L. Garrison, Ashley E. Frakes

This study identifies FLP-17, a neuropeptide that mediates cell non-autonomous UPRER activation in C. elegans, protecting against ER stress and protein aggregation.

bioRxiv · Mar 14, 2025 · PreprintNeuroscience

Identifying the function of the NMDA NR1C2 subunit through its interaction with Magi-2 during inflammatory pain

Garrett D. Sheehan, Molly K. Martin, Adam Roszczyk, Katherient Hao, Arin Bhattacharjee

The paper identifies NR1C2's role in inflammatory pain by showing its regulation via Magi-2 and Nedd4-1 ubiquitin ligase, and demonstrates pharmacological targeting of NR1C2.

bioRxiv · Jan 30, 2024 · PreprintNeuroscience