Author

Laetitia Pericou

Centre Hospitalier Universitaire Vaudois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Bili SeijoiD· 1 shared George CoukosiD· 1 shared Isaac CrespoiD· 1 shared Melita B. IrvingiD· 1 shared Romain Vuillefroy de SillyiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCell Biology

Bili SeijoORCID

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1 paper

Recent·Most cited

Cell BiologyThe EMBO JournalPeer-reviewedSep 16, 2024

Acidity-induced dysfunction of CD8+ T cells is characterized by impaired IL-2 responsiveness and perturbations to mTORC1 signaling and c-Myc levels

Romain Vuillefroy de Silly, Laetitia Pericou, Bili Seijo…·Melita B. Irving

This study shows that low pH impairs CD8+ T cell function by reducing IL-2 responsiveness, disrupting mTORC1 signaling, and altering c-Myc levels and amino acid metabolism.

51 citationstop 2%

humanproteomics

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