Seizure-related gene 6 (SEZ6) encodes a Cancer stem cell-specific proangiogenic molecule: A novel glioma therapeutic target
Arani Mukherjee, Shreoshi Sengupta, Abhishek Chowdhury, Lakshay Garg, Kaval Reddy Prasasvi, Parimal Mishra, Dhrubjyoti Sharma, Subhrodeep Saha, Jayanta Chatterjee, Parichay J. Perikal, Sunil Valentine Furtado, Vijay Thiruvenkatam, Sivapriya Kirubakaran, Kumaravel Somasundaram
This study identifies SEZ6 as a glioma stem cell-specific proangiogenic molecule that promotes angiogenesis through TGFβ signaling, offering a novel therapeutic target for glioblastoma.
bioRxiv · Jul 16, 2026 · PreprintCancer Biology