Laura A. Lynch

Striatal pathways oppositely shift cortical activity along the decision axis

The paper investigates how direct and indirect basal ganglia pathways influence cortical activity during decision-making, finding that they oppositely modulate a subset of neurons encoding decision variables.

A neural mechanism for learning from delayed postingestive feedback

The paper shows that postingestive malaise signals reactivate amygdala flavor representations, strengthening memory and resolving temporal credit assignment in aversive learning.

Precise calcium-to-spike inference using biophysical generative models

The paper develops biophysically-inspired models to improve spike inference from calcium imaging by accounting for kinetic features of fluorescent indicators.

Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility

The paper shows that heightened lateral habenula activity during stress leads to lasting brainwide and behavioral susceptibility in mice.

Multi-region coordination of evidence accumulation and decision commitment in the brain

This study investigates decision-making phases in the brain using simultaneous recordings, supporting a single accumulator model and revealing abrupt covert commitment transitions.