Author

Laura‐Maria Oja

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alison GoateiD· 2 shared Kathryn R. BowlesiD· 2 shared Abhijeet SharmaiD· 1 shared Ana C. PereiraiD· 1 shared Benjamin M. Jadow· 1 shared Chiara PediconeiD· 1 shared DA Pugh· 1 shared Derian A. Pugh· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Alison GoateORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 2, 2023

Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function

Kathryn R. Bowles, DA Pugh, Chiara Pedicone…·Alison Goate

This study develops isogenic iPSC lines with MAPT S305 mutations to increase 4R tau expression, revealing altered neuronal and astrocytic functions in tauopathies.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceActa NeuropathologicaPeer-reviewedDec 7, 2021

Dysregulated coordination of MAPT exon 2 and exon 10 splicing underlies different tau pathologies in PSP and AD

Kathryn R. Bowles, Derian A. Pugh, Laura‐Maria Oja…·Alison Goate

The paper identifies dysregulated coordination of MAPT exon 2 and exon 10 splicing in Alzheimer's and progressive supranuclear palsy, leading to distinct tau isoform accumulation.

32 citations

humanbulk RNA-seq

𝕏 PostBluesky