A comprehensive analysis of humanized mouse models for the study of cancer immunotherapies
Philippe De La Rochère, Laure Loumagne, Mélanie Rathaux, Marine Dubois, Jordan Denizeau, Fariba Némati, Sophie Viel, Dario Rocha, Tamara Slavnic, Jayant Thatted, Christine Sedlik, Xuesong Ouyang, Didier Decaudin, Georges A. Azar, Sukhvinder Sidhu, Eliane Piaggio
This study compares two humanized mouse models for cancer immunotherapies, finding differences in immune cell engraftment and tumor response to T-cell-directed therapies.
Frontiers in Immunology · Apr 7, 2026Peer-reviewedImmunology