Fariba Némati

This study compares two humanized mouse models for cancer immunotherapies, finding differences in immune cell engraftment and tumor response to T-cell-directed therapies.

This paper shows that the SF3B1 inhibitor pladienolide B inhibits DNA damage repair and counteracts platinum resistance in NSCLC by inducing genomic instability and altering DNA repair gene splicing.

This study shows that ATRX mutation type affects chromatin response to retinoic acid in neuroblastoma, influencing differentiation and therapeutic response.

The paper uses multi-omics analysis to compare malignant and normal uveal melanocytes, identifying genomic instability and a BAP1 promoter deletion as key features of uveal melanoma.