Author

Laurel S. Kleppe

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Chan‐Il Choi· 1 shared Claudia C.S. ChiniiD· 1 shared Claudia Francesca LucchinettiiD· 1 shared Eduardo N. ChiniiD· 1 shared Hyesook Yoon· 1 shared Isobel A. ScarisbrickiD· 1 shared Monica Renee LangleyiD· 1 shared Thais PeclatiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Chan‐Il Choi

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1 paper

Recent·Most cited

Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration

Monica Renee Langley, Chan‐Il Choi, Thais Peclat, Yong Guo, Whitney L. Simon, Hyesook Yoon, Laurel S. Kleppe, Claudia Francesca Lucchinetti, Claudia C.S. Chini, Eduardo N. Chini, Isobel A. Scarisbrick

This study shows that CD38 in astrocytes mediates NAD+ depletion and myelin damage caused by high fat diets and demyelination, with CD38 inhibitors improving myelin regeneration.

Journal of Neuroscience · Sep 7, 2021Peer-reviewedNeuroscience