Author

Whitney L. Simon

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron J. JohnsoniD· 1 shared Anthony D. UmpierreiD· 1 shared Benjamin Hur· 1 shared Bohan LiiD· 1 shared Chan‐Il Choi· 1 shared Claudia C.S. ChiniiD· 1 shared Claudia Francesca LucchinettiiD· 1 shared Dale B. BoscoiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aaron J. JohnsonORCID

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2 papers

Recent·Most cited

Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis

Anthony D. Umpierre, Bohan Li, Katayoun Ayasoufi, Whitney L. Simon, Shunyi Zhao, Manling Xie, Grace Thyen, Benjamin Hur, Jiaying Zheng, Yue Liang, Dale B. Bosco, Mark Andrew Maynes, Zhaofa Wu, Xinzhu Yu, Jaeyun Sung, , Long‐Jun Wu

The paper identifies UDP-P2Y6 signaling as a key driver of microglial calcium activity, phagocytosis, and neuroinflammation during epileptogenesis.

Neuron · Apr 12, 2024Peer-reviewedNeuroscience

Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration

Monica Renee Langley, Chan‐Il Choi, Thais Peclat, Yong Guo, Whitney L. Simon, Hyesook Yoon, Laurel S. Kleppe, Claudia Francesca Lucchinetti, Claudia C.S. Chini, Eduardo N. Chini, Isobel A. Scarisbrick

This study shows that CD38 in astrocytes mediates NAD+ depletion and myelin damage caused by high fat diets and demyelination, with CD38 inhibitors improving myelin regeneration.

Journal of Neuroscience · Sep 7, 2021Peer-reviewedNeuroscience