Author

Lauren Togonon Arayan

Jackson Laboratory

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Immunology· 1

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Jing WeniD· 1 shared Kristian Lorenzo· 1 shared Leonard D. ShultziD· 1 shared Lisa M. BurzenskiiD· 1 shared Timothy M. StearnsiD· 1 shared Vishnu HosuriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperImmunology

Jing WenORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJun 1, 2026

Redundant γc cytokines license IL-1-driven neutrophil inflammation through MEK/ERK convergence

Kristian Lorenzo, Lauren Togonon Arayan, Timothy M. Stearns…·Vishnu Hosur

This study identifies redundant γc cytokines that enhance IL-1-driven neutrophil inflammation via MEK/ERK convergence, showing that blocking the shared γc receptor or MEK/ERK reduces disease severity.

DOI 10.64898/2026.05.28.728506

mouseproteomics

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