Timothy M. Stearns

Redundant γc cytokines license IL-1-driven neutrophil inflammation through MEK/ERK convergence

This study identifies redundant γc cytokines that enhance IL-1-driven neutrophil inflammation via MEK/ERK convergence, showing that blocking the shared γc receptor or MEK/ERK reduces disease severity.

Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans

The paper identifies host genetic factors influencing anti-PD-1 response in mice and humans by mapping QTLs and finding a core gene network with prognostic value in human tumors.

Characterization of an Osmr Conditional Knockout Mouse Model

The paper characterizes an Osmr conditional knockout mouse model, showing variable tissue-dependent effects on OSMR mRNA and protein expression.

A novel mouse model expressing human forms for complement receptors CR1 and CR2

This paper creates a mouse model expressing human CR1 and CR2 variants to study their role in disease.