Hepatic ADMA/PRMT1 axis regulation is associated with NO-dependent endothelial dysfunction in MASH
Justine Lallement, Sébastian Bott, Hrag Esfahani, Kristian Serafimov, Maxence Henderson, Zoé Benoit, Laurent Dumas, Sultan Al‐Siyabi, Olivier Féron, Isabelle Anne Leclercq, Chantal Dessy
This study investigates how MASH impairs endothelial function via NO-dependent mechanisms and identifies ADMA as a key liver-derived mediator.
bioRxiv · Jun 10, 2025 · PreprintPhysiology