Author

Laurent Guillou

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Philippe BrabetiD· 2 shared Aurélie Cubizolle· 1 shared Béatrice BocquetiD· 1 shared Bertrand MollereauiD· 1 shared Carla Sanjurjo-SorianoiD· 1 shared Christophe HirtziD· 1 shared Claire Angebault-Prouteau· 1 shared Daan M Van Den Brink· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Philippe BrabetORCID

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2 papers

Recent·Most cited

Dual CRALBP isoforms unveiled: iPSC-derived retinal modelling and AAV2/5-RLBP1 gene transfer raise considerations for effective therapy

Krishna Damodar, Grégor Dubois, Laurent Guillou, Daria V. Mamaeva, Marie O. Péquignot, Nejla Erkilic, Carla Sanjurjo-Soriano, Hassan Boukhaddaoui, Florence Bernex, Béatrice Bocquet, Jérôme Vialaret, Yvan Arsenijévic, T. Michael Redmond, Christophe Hirtz, Isabelle Meunier, , Vasiliki Kalatzis

The paper models RLBP1-related retinal diseases using iPSC-derived RPE and validates a gene replacement strategy, identifying a novel CRALBP isoform with functional significance.

Molecular Therapy · Oct 9, 2024Peer-reviewedMolecular Biology

Expression of fatty acid transport protein in retinal pigment cells promotes lipid droplet expansion and photoreceptor homeostasis

Daan M Van Den Brink, Aurélie Cubizolle, Gilles Chatelain, Francesco Napoletano, Pierre Dourlen, Nathalie Davoust, Laurent Guillou, Claire Angebault-Prouteau, Nathalie Bernoud-Hubac, Michel Guichardant, Philippe Brabet, Bertrand Mollereau

This study shows that fatty acid transport protein in retinal pigment cells promotes lipid droplet expansion, which supports photoreceptor homeostasis under normal conditions but can be toxic under pathological stress.

bioRxiv · Mar 23, 2018 · PreprintCell Biology