T. Michael Redmond

The paper presents the structure and functional properties of a BCOL protein from the lancelet Branchiostoma floridae, revealing structural and sequence differences from other CCDs.

This study demonstrates the successful integration and function of human iPSC-derived microglia in the mouse retina, mimicking endogenous microglial behavior and suggesting therapeutic potential for retinal diseases.

The paper models RLBP1-related retinal diseases using iPSC-derived RPE and validates a gene replacement strategy, identifying a novel CRALBP isoform with functional significance.

The paper describes a potential therapy for PCDH15-associated Usher syndrome using exogenous retinoids in a mouse model, showing improved ERG amplitudes.