Author

Le Jin Sun

Moffitt Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Florian A. KarrethiD· 1 shared Gina M. DeNicolaiD· 1 shared H. Carlo MaureriD· 1 shared Kenneth P. OliveiD· 1 shared Matthew LongiD· 1 shared Samantha CaldwelliD· 1 shared Yumi KimiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Florian A. KarrethORCID

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1 paper

Recent·Most cited

PHGDH is a targetable driver of PDAC progression

Yumi Kim, Le Jin Sun, Matthew Long, Samantha Caldwell, H. Carlo Maurer, Kenneth P. Olive, Florian A. Karreth, Gina M. DeNicola

This study identifies PHGDH as a driver of PDAC progression by maintaining glutamine metabolism and mTOR signaling, revealing a therapeutic vulnerability to glutamine antagonism in PHGDH-deficient tumors.

bioRxiv · Mar 14, 2026 · PreprintCancer Biology