Author

Le Xiong

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Akane KawaguchiiD· 1 shared Atsushi ToyodaiD· 1 shared Hiroshi OchiaiiD· 1 shared Kako NakazatoiD· 1 shared Katsuhiko MinamiiD· 1 shared Kazuhiro MaeshimaiD· 1 shared Ken KurokawaiD· 1 shared Koichi HigashiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Akane KawaguchiORCID

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1 paper

Recent·Most cited

Cohesin prevents local mixing of condensed euchromatic domains in living human cells

Masa A. Shimazoe, Shiori Iida, Katsuhiko Minami, Koichi Higashi, Sachiko Tamura, Yoshiaki Kobayashi, Shin Fujishiro, Le Xiong, Kako Nakazato, S. S. Ashwin, Tomoko Nishiyama, Yu Nagata, Masato T. Kanemaki, Akane Kawaguchi, Yasuyuki Ohkawa, , Kazuhiro Maeshima

This study shows cohesin maintains condensed euchromatic domains in human cells by preventing local mixing, which is crucial for transcriptional insulation.

Nature Genetics · Sep 1, 2026Peer-reviewedCell Biology