ImmunologybioRxivPreprint
Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype.
Mathilde Cheray, Adriana‐Natalia Murgoci, Adamantia F. Fragopoulou…·Bertrand Joseph
This study shows that glioma-induced DNMT3A reduction in microglia leads to DNA demethylation and an anti-tumoral phenotype, suggesting DNMT3A as a therapeutic target for glioblastoma.
DOI 10.1101/2025.02.22.639606