Author

Carlos Fernando Dias Rodrigues

Karolinska InstitutetORCID 0000-0003-1685-9883Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Adamantia F. FragopoulouiD· 2 shared Ahmed M. OsmaniD· 2 shared Bertrand JosephiD· 2 shared Klas BlomgreniD· 2 shared Lara FrießiD· 2 shared Lena-Maria Carlson· 2 shared Adriana‐Natalia MurgociiD· 1 shared Alejandro Lastra RomeroiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersImmunology

Adamantia F. FragopoulouORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Glioma-induced DNMT3A-dependent reduction of DNA methylation in microglia promotes a transient anti-tumoral phenotype.

Mathilde Cheray, Adriana‐Natalia Murgoci, Adamantia F. Fragopoulou, Carlos Fernando Dias Rodrigues, Martin Škandík, Ahmed M. Osman, Christine Hong, Guillermo Vázquez-Cabrera, Lara Frieß, Lena-Maria Carlson, Shigeaki Kanatani, Yue Li, Anastasios E. Damdimopoulos, Per Uhlén, Fredrik Kamme, , Bertrand Joseph

This study shows that glioma-induced DNMT3A reduction in microglia leads to DNA demethylation and an anti-tumoral phenotype, suggesting DNMT3A as a therapeutic target for glioblastoma.

bioRxiv · Feb 22, 2025 · PreprintImmunology

Microglia Adopt Temporally Specific States after Irradiation, Correlating with Neuronal Asynchrony

Alejandro Lastra Romero, Efthalia Preka, Giusy Pizzirusso, Luis Enrique Arroyo‐García, Georgios Alkis Zisiadis, Nuria Oliva‐Vilarnau, Yana Ruchiy, Thea Seitz, Kai Zhou, Arturo G. Isla, Lara Frieß, Ying Sun, Maria Querol Canut, Alia Shamikh, Yiran Xu, , Klas Blomgren

This study tracks microglial state changes and neuronal asynchrony after irradiation in mice, showing delayed microglial responses and two phases of neuronal dysfunction.

bioRxiv · Feb 15, 2025 · PreprintNeuroscience