Author

Leonie Sowoidnich

Leipzig University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Charlotte J. SumneriD· 3 shared Christian M. SimoniD· 3 shared Florian GerstneriD· 2 shared Livio PellizzoniiD· 2 shared Vanessa Dreilich· 2 shared Aaron L. Norman· 1 shared Adela Vankova· 1 shared Amy K. SmithiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Charlotte J. SumnerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A standardized framework resolves ambiguity in motor neuron loss across neurodegenerative diseases

Leonie Sowoidnich, Aaron L. Norman, Florian Gerstner, Josiane K. Siemund, Jannik M. Buettner, John G. Pagiazitis, Vanessa Dreilich, Konstantin Pilz, Dajun Tian, Charlotte J. Sumner, Angela Paradis, George Z. Mentis, Christian M. Simon

This paper develops a standardized framework to accurately quantify motor neuron loss across neurodegenerative diseases by addressing variability in sampling and marker specificity.

Acta Neuropathologica Communications · Sep 1, 2026Peer-reviewedNeuroscience

Incomplete cerebellar circuit restoration limits functional recovery following SMN therapy in severe spinal muscular atrophy

Sayan Ruwald, Adela Vankova, Frieda Hanschmann, Christian Menedo, Sandra Wittig, Marie L Stephan, Vanessa Dreilich, Severine Ruetze, Amy K. Smith, Leonie Sowoidnich, Christian Geis, Stefan Hallermann, Charlotte J. Sumner, Livio Pellizzoni, Beatriz Blanco-Redondo, , Christian M. Simon

The paper identifies cerebellar pathology as a conserved yet distinct feature in severe SMA, showing divergent therapeutic outcomes with SMN-restoring therapies.

bioRxiv · Aug 19, 2026 · PreprintNeuroscience

A p53-ΔNp73 signaling axis drives selective motor neuron degeneration in spinal muscular atrophy

Maria Jose Carlini, Xuemei Hu, Leonie Sowoidnich, Archana Yadav, Jorge García, Maria Savin, Charlotte J. Sumner, Vilas Menon, Christian M. Simon, Livio Pellizzoni

This study identifies a p53-ΔNp73 signaling axis that drives motor neuron degeneration in SMA, revealing a context-dependent switch in p53 family signaling that promotes neurodegeneration.

bioRxiv · Jun 25, 2026 · PreprintNeuroscience