Author

Lev Tsidilkovski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Garegin A. PapoianiD· 2 shared Hayk Saribekyan· 2 shared Tigran M. AbramyaniD· 2 shared Alfonso LopeziD· 1 shared Aram DavtyaniD· 1 shared Arman Fahradyan· 1 shared Arman SimonyaniD· 1 shared Ashot Papoyan· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiophysics

Garegin A. PapoianORCID

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Author profile →

2 papers

Recent·Most cited

Overcoming the accuracy-generalization tradeoff in docking and scoring for prospective virtual screening

Garik Petrosyan, Vahagn Altunyan, Tsolak Ghukasyan, Tigran M. Abramyan, Grigor Arakelov, Aram Davtyan, Tigran Aghajanyan, Iskander Nakipov, Gagik Navasardyan, Arman Fahradyan, Hazarapet Tunanyan, Arman Simonyan, Paweł Janczyk, DAS Silva, Hayk Saribekyan, , Garegin A. Papoian

This paper introduces DODock and DOScore, hybrid ML/physics frameworks for docking and scoring that improve accuracy while generalizing better to novel molecules, showing significant improvements in hit rates for virtual screening.

bioRxiv · Aug 3, 2026 · PreprintBiophysics

Deep Mutational Scanning Reveals EGFR Mutations Conferring Resistance to the 4th-generation EGFR tyrosine kinase inhibitor BLU-945

Yueyang Wang, Yuan Hao, Michela Ranieri, Tigran M. Abramyan, Lev Tsidilkovski, Michelle Hollenberg, Alfonso Lopez, Xavier T.R. Moore, Fiona Sherman, Jiehui Deng, Hayk Saribekyan, Garegin A. Papoian, Kwok‐Kin Wong, Elaine Shum, John Thomas Poirier

This study identifies EGFR mutations conferring resistance to BLU-945 using deep mutational scanning and shows that combination treatment may suppress resistance mechanisms.

npj Precision Oncology · Aug 20, 2025Peer-reviewedCancer Biology