Yueyang Wang

The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.

This study identifies EGFR mutations conferring resistance to BLU-945 using deep mutational scanning and shows that combination treatment may suppress resistance mechanisms.

This paper enhances the Eco1 retron editor for precise genome editing in human cells by improving ncRNA stability and reducing sgRNA extension, achieving editing without double-strand breaks.