Author

Levan Jugheli

Swiss Tropical and Public Health Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Sébastien GagneuxiD· 4 shared Sònia BorrelliD· 4 shared Galo Adrián GoigiD· 3 shared Kakha MchedlishviliiD· 3 shared Maia KipianiiD· 3 shared Nestani TukvadzeiD· 3 shared Nino MaghradzeiD· 3 shared Rusudan Aspindzelashvili· 3 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

Sébastien GagneuxORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Within-host evolution of drug tolerance in Mycobacterium tuberculosis.

Valerie F. A. March, Kakha Mchedlishvili, Galo Adrián Goig, Nino Maghradze, Teona Avaliani, Rusudan Aspindzelashvili, Zaza Avaliani, Maia Kipiani, Nestani Tukvadze, Levan Jugheli, Selim Bouaouina, Anna Doetsch, Sevda Kalkan, Miriam Reinhard, Sébastien Gagneux, Sònia Borrell

This study investigates how antibiotic tolerance evolves in Mycobacterium tuberculosis during treatment and finds no evidence that it contributes to delayed culture conversion.

JAC-Antimicrobial Resistance · Jan 7, 2026Peer-reviewedMicrobiology

Clinical and bacterial determinants of unfavorable tuberculosis treatment outcomes: an observational study in Georgia

Galo Adrián Goig, Chloé Loiseau, Nino Maghradze, Kakha Mchedlishvili, Teona Avaliani, Ana Tsutsunava, Daniela Brites, Sevda Kalkan, Sònia Borrell, Rusudan Aspindzelashvili, Zaza Avaliani, Maia Kipiani, Nestani Tukvadze, Levan Jugheli, Sébastien Gagneux

This study identifies patient and bacterial factors associated with unfavorable tuberculosis treatment outcomes in Georgia using genomic and clinical data from 4,536 patients.

Genome Medicine · Nov 14, 2025Peer-reviewedGenetic & Genomic Medicine

Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis.

Valerie F. A. March, Nino Maghradze, Kakha Mchedlishvili, Teona Avaliani, Rusudan Aspindzelashvili, Zaza Avaliani, Maia Kipiani, Nestani Tukvadze, Levan Jugheli, Selim Bouaouina, Anna Doetsch, Galo Adrián Goig, Sébastien Gagneux, Sònia Borrell

The paper shows that antibiotic treatment affects Mycobacterium tuberculosis culturability, with differential effects on colony formation and liquid culture growth.

Scientific Reports · Jan 28, 2025Peer-reviewedMicrobiology

Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim

Fabrizio Menardo, Liliana K. Rutaihwa, Michaela Zwyer, Sònia Borrell, Iñaki Comas, Emilyn Costa Conceição, Mireia Coscollá, Helen Suzanne Cox, Moses Lutaakome Joloba, Horng-Yunn Dou, Julia Feldmann, Lukas Fenner, Janet Fyfe, Qian Gao, Darı́o Garcı́a de Viedma, , Sébastien Gagneux

The paper analyzes whole genome sequences of Mycobacterium tuberculosis lineages L1 and L3 to show South Asia's role in their dispersion and identify local adaptation at the esxH locus.

F1000Research · Feb 1, 2021Peer-reviewedGenomics