Zaza Avaliani

Within-host evolution of drug tolerance in Mycobacterium tuberculosis.

This study investigates how antibiotic tolerance evolves in Mycobacterium tuberculosis during treatment and finds no evidence that it contributes to delayed culture conversion.

Clinical and bacterial determinants of unfavorable tuberculosis treatment outcomes: an observational study in Georgia

This study identifies patient and bacterial factors associated with unfavorable tuberculosis treatment outcomes in Georgia using genomic and clinical data from 4,536 patients.

Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis.

The paper shows that antibiotic treatment affects Mycobacterium tuberculosis culturability, with differential effects on colony formation and liquid culture growth.

Genetic diversity within diagnostic sputum samples is mirrored in the culture of Mycobacterium tuberculosis

This study shows that culturing Mycobacterium tuberculosis from sputum samples accurately mirrors the genetic diversity found in the original clinical samples, with high variant agreement and correlation.