Author

Leyla Teos

University of California, Davis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aisha Saiyed· 1 shared Dmitry A. GoncharoviD· 1 shared Elena A. GoncharovaiD· 1 shared Horace Michael DeLisseriD· 1 shared Iryna ZhyvyloiD· 1 shared John R. GreenlandiD· 1 shared Lifeng JiangiD· 1 shared Lisa M. FranziiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aisha Saiyed

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1 paper

Recent·Most cited

Lactate dehydrogenase-induced DNA Topoisomerase 1 is a novel regulator of smooth muscle cell proliferation and remodeling in pulmonary arterial hypertension

Lifeng Jiang, Iryna Zhyvylo, Dmitry A. Goncharov, Tapan Dey, Neil J. Kelly, Leyla Teos, Lisa M. Franzi, Aisha Saiyed, Nicholas J. Kenyon, John R. Greenland, Paul J. Wolters, Stephen Y. Chan, Horace Michael DeLisser, Tatiana V. Kudryashova, Elena A. Goncharova

This study identifies LDHA-lactate-induced over-lactylation and TOP1 accumulation as drivers of PASMC hyper-proliferation and PAH, with TOP1 inhibition reversing these effects.

bioRxiv · Nov 10, 2025 · PreprintCell Biology